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In vitro assays

Even if alternatives exist, radiometric assay remains the gold standard for many scientists. Whatever the binding assay (involving cells, coated antigens, cells fragments...), we propose our dedicated facilities and our expertise to assist you.

In vitro assays service includes (but are not limited to):

- Binding assays
- Internalization assays

- Cytotoxicity assays

- Blood to plasma ratio assays

Exemple: radioactive binding assays will allow to determine the dissociation constant (Kd) of the labelled molecule and the inhibition constant (Ki) and IC50 of the non-radioactive molecule. Receptor density (Bmax) can also be obtained.


Saturation binding experiments measure equilibrium binding of various concentrations of the radioligand.


Competitive binding experiments measure equilibrium binding of a single concentration of radioligand at various concentrations of an unlabeled competitor